![]() Further work is required to define species-specific reference intervals for cTnI. In conclusion, the assessment of cTnI using the i-STAT®1 hand-held analyser shows promise as a humoral marker of cardiac pathology in mammalian species but not for avian and reptilian species. ABBOTT I-Stat Troponin I Cartridge Test 25 Count Bx ABBOTT-03P9025 This product is a refrigerated product and refrigerated shipping. Test Code: TIWB Clinical Information: Only available in rural Manitoba. All avian and reptilian samples were below 0.00 µg/L even though overt cardiac pathology was noted in some of these animals. Laboratory: Clinical Biochemistry Test Name: TROPONIN I (iSTAT) - (B). The majority of animals with concentrations of cTnI above 0.08 µg/L were subsequently shown to have pathology with potential cardiac involvement. Performed at authorized locations by point of care operators. Concentrations of cTnI below, equal to and well above a suggested cut-off of 0.08 µg/L were observed in mammalian species. Abbott i-Stat - two-site enzyme-linked immunosorbent assay (ELISA) Test Usage. During routine health checks at the Zoological Society of London, 171 blood samples were collected from 36 different species (27 mammal, seven bird and two reptile) and were analysed for cTnI using the i-STAT®1 hand-held analyser. The secondary aim was to explore whether elevations in cTnI were related to underlying cardiac pathology. The primary aim of this feasibility study was to determine whether the i-STAT®1 hand-held analyser can be used to identify elevations of serum and plasma cTnI in a variety of non-domestic species. Recent advances in human and domestic animal medicine have shown cardiac troponin I (cTnI) to be the biomarker of choice for myocardial damage. Although over the past 15 years the diagnostic performance of the previous gold-standard assay, creatine kinase-MB, has not changed appreciably, the ever-increasing sensitivity of cTn assays has had a dramatic impact on the use of cTn testing to diagnose ACS. evaluating the performance of the RAMP Troponin I test on the RAMP 200 versus the Abbott i-STAT cardiac troponin (cTnI) Immunoassay, the Quidel Triage. However due to the wide range of species dealt with and their different sizes, few techniques have been validated. Cardiac troponin (cTn) testing is an essential component of the diagnostic workup and management of acute coronary syndromes (ACS). In the field of cardiology the diagnostic techniques used for domestic animals are also applied to exotic species. One of the main challenges faced by veterinary surgeons in the field of zoo and wild animal medicine is the lack of published reference data and validated tests for non-domestic species. International Primate Heart Project, Cardiff Metropolitan University ![]() St Georges University Hospitals NHS Foundation Trust Zoological Society of London and International Primate Heart Project, Cardiff Metropolitan University Using i-STAT troponin Normal 0.04 microgram/L Elevated > 0.04 microgram/L This differs from the laboratory high sensitivity troponin assay.
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